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Simcyp diltiazem model v.21
Diltiazem Model V.21, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/diltiazem+model+v%2E21/diltiazem+model+v+21/pm38481038-97-1-9
Average 90 stars, based on 1 article reviews
diltiazem model v.21 - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Understanding CYP3A4 and P‐gp mediated drug–drug interactions through PBPK modeling – Case example of pralsetinib
Article Snippet: For diltiazem, the P‐gp inhibition (not included in Simcyp default diltiazem model [V.21], although clinically known) was added into the model (P‐gp Ki = 0.01 uM) based on verification simulations with diltiazem and a known P‐gp substrate, digoxin, as detailed in the Supplementary Material .

Article Title: Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib.
Article Snippet: For voriconazole, a Simcyp validated PBPK model (included for the first time in Simcyp version V.22) was obtained and used after verification in V.21 for this purpose.



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Simcyp diltiazem model v.21
Diltiazem Model V.21, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/diltiazem+model+v%2E21/diltiazem+model+v+21/pm38481038-97-1-9
Average 90 stars, based on 1 article reviews
diltiazem model v.21 - by Bioz Stars, 2026-09
90/100 stars
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